Excess serum osmolality gap after ingestion of methanol: a methodology-associated phenomenon?

Excess serum osmolality gap after ingestion of methanol: a methodology-associated phenomenon?

A patient intentionally ingested an unknown amount of methanol and was admitted to the hospital 6 h later. On admission, the methanol concentration in blood was estimated as approximately of 134 mmol/L, based on the calculation of the osmolal gap. Intravenous ethanol administration and hemodialysis were promptly started. During hemodialysis, several blood samples were collected for determinatio...

Method-specific reference intervals for serum anion gap and osmolality.

To the Editor: We wish to comment on reference intervals for the serum anion gap and osmolality. The serum anion gap, which is most commonly defined as AG 5 Na-Cl-TCO2, traditionally has had a reference interval of 8 –16 mmol/L with a mean value (i.e., mean of values used to determine its reference interval) of 12 mmol/L (1, 2). In a recent report (3), the stated reference interval for the anio...

Accidental methanol ingestion: Case report

BACKGROUND The incidence of methanol (CH3OH) intoxication differs enormously from country to country. Methanol intoxication is extremely rare in the Dutch population. Even a low dose can already be potentially lethal. Patients are conventionally treated with hemodialysis. Therefore we'd like to present a report of a foreign sailor in Rotterdam who accidentally caused himself severe methanol int...

Alcohol intoxication and serum osmolality.

The relation between serum osmolality and blood-alcohol was studied prospectively in 565 acute trauma patients. The two measurements were closely correlated. It is therefore possible to estimate the blood-alcohol from serum osmolality to assist in the clinical management of acutely injured patients.

Excess Carrier Phenomenon in Semiconductors